basics of immunology ppt

Antigen-presenting cells are functionally-defined cells that are able too initiate adaptive immune responses by presenting antigen to T cells. - Title: Course of Immunology - introduction Author: uzivatel Last modified by: budinsky Created Date: 9/22/2013 6:36:19 PM Document presentation format. Rutgers, The State University of New Jersey and New Jersey Medical School Including ontogeny, the innate immune system, MHC & antigen presentation, T cells, B cells and antibodies I have here presented fifteen Multiple Choice Questions from the Immunology sections. The immune system responds to any antigen, Everyones immune system is different, and reacts, a. plasma (the yellow liquid component of blood, b. hematocrit (proportion of blood volume that, http//www.youtube.com/watch?vlrYlZJiuf18feature, Are different from B and NK cells because they, A Helper T cell which divides rapidly and, A Cytotoxic T cell which destroys virally, A Memory T cell which remain active after an, A Regulatory T cell which is responsible for, A Natural Killer T cell which is responsible, Their primary role is to make antibodies to, Flow Cytometry relates to immunology because it, Clinics and hospitals use Flow Cytometry to test. T: +44 (0)20 3019 5901 Â, Daniel Price, British Society for Immunology, UK, Studying immunology at undergraduate level, Studying immunology at postgraduate level, EFIS Young Immunologists Task Force (yEFIS). •The immune system plays a huge role in protecting against infection and cancers •The cells of the innate immune system recognize pathogens by PRRs •They are also activated by DAMPs •The inflammasome is made up by a group of PRRs called the NOD like receptors •They produce IL-1βand IL-18 which are potent mediators of inflammation and are responsible for the occurrence of many … If they encounter antigen that they recognise, this indicates infection or malignancy, and they are then able to induce apoptosis (autodestruction) of targeted body cells. In particular, they play a key role in the so-called allergic response. - Immunology for Surgeons: The Basics 101 Principles of Surgery Jeff Warren, MD, FRCSC October 19, 2010 Objectives The Players -- T-cells and B-cells Immunoglobulins ... - Chapter 1 The Basics of Understanding Nutrition, - Title: No Slide Title Last modified by: Regueiro Created Date: 9/23/1998 2:01:52 PM Document presentation format: Presentaci n en pantalla Other titles, - Rheumatology: Back to Basics: 2010 James Gillray The Gout 1799, - Title: transplantation Subject: 7year Author: wangqun Last modified by: Saverio Minucci Created Date: 9/9/2003 3:55:24 AM Document presentation format, - INTRODUCTION TO IMMUNOLOGY Ahmad Sh. Once activated, B cells differentiate into plasma cells that are capable of secreting antibody molecules into the circulation (small molecules that match the individual specificity of the parent cell) that are then able to find their targets elsewhere in the body. For that reason, the gene complex was termed the ‘‘major histocompatibility complex.’’ MHC genes (called the H-2 complex in mice) were first recognized in 1937 as a barrier to transplantation in mice. Once activated, the member proteins assemble to form complexes on the surface of microbes that punch holes in the membrane. It includes audio as well as the presentation slides. The immune system is designed to protect the body from pathogens. Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Both systems work in close cooperation and, to an important extent, the adaptive immune system relies upon the innate immune system to alert it to potential targets, and shape its response to them. Both of these receptor types interact with TCRs. Department of Pathology and Laboratory Medicine . • Immunity. 34 Immunology and Transplants 36 Immunity and Cancer 39 The Immune System and the Nervous System 40 Frontiers in Immunology 45 Summary 47 Glossary . Detection of Estrogen and IL-17A Levels in Serum of Premenopausal and Postmenopausal Women in Kirkuk City Iraq 2. University Children s Hospital of Vienna, Austria. Adaptive immunity utilises many kinds of receptor to coordinate its activities. Or use it to create really cool photo slideshows - with 2D and 3D transitions, animation, and your choice of music - that you can share with your Facebook friends or Google+ circles. Body cells are continuously processing protein derived from the internal cellular environment and presenting it in association with MHC class I receptors. inflammation) in the tissues and home-in on infective bacteria before neutralising and engulfing them (‘phagocytosis’). Feel free to contact the Admin if you have any doubts or quires. Immunology. PowerShow.com is a leading presentation/slideshow sharing website. The Basics of Immunology: An Introductory Unit for High School Junior and Senior Students . dr Emina Savi Prof. dr Vera Pravica imunologija@med.bg.ac.rs Tel. Vaccines can utilise harmless elements from particular pathogens to prime the immune system, so that if the pathogen is actually encountered, it is met with a stronger secondary (‘memory’) response and dealt with more quickly. – State of being able to resist a particular infection or toxin. The lymphatic system is a system of vessels draining fluid (derived from blood plasma) from body tissues. DCs may be activated by local innate immune signals (induced by infection) causing them to migrate through the lymph (or blood) to lymph nodes where they present antigen to T cells. If a protein fragment is recognised by a particular cytotoxic T cell this will suggest that it is of foreign origin (due to elimination of cells recognising ‘’self’’) leading to a cellular adaptive response. As already stated, B cells can recognise antigen through direct recognition of antigen via their BCRs, without the need for prior processing or presentation via a receptor – so they are key to identifying extracellular pathogens (e.g. Mast cells and basophils are innate cell types that, when activated, secrete histamine, which can be an important inflammatory mediator produced in response to initial tissue damage as a result of infection. 1. Examples include severe combined immunodeficiency (SCID) and common variable immunodeficiency (CVID). Basic Immunology (2016 May) - Jennifer Lee PhD - Duration: 42:14. the skin), enhanced by substances secreted by the body, such as saliva and tears, that contain molecules that can neutralise bacteria. Academia.edu is a platform for academics to share research papers. Important initial barriers to infection are physical (e.g. Basic Immunology focuses on substances that take part in serological reactions, including antigens, antibodies, and the physicochemical nature of immunological reactions. Identification of the important role of the MHC in allowing the body to discriminate between self/non-self tissues has greatly enhanced the success of tissue and organ transplantation, by allowing tissue matching. Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Building asilmi@iugaza.edu.ps Office hours: Every week Sun &Tues 11:00 to 12:00. The Basics of Immunology Guide Background Information Our amazing immune system protects our bodies from bacteria, viruses, and other harmful pathogens. Skinner 14 April 2010 ... - ... www.w3.org/1999/02/22-rdf-syntax-ns#' xmlns:iX='http://ns.adobe.com/iX/1.0 ... xmlns:xapMM='http://ns.adobe.com/xap/1.0/mm ... - IMMUNOLOGY Doc. Journal of immunology provides current research information in basic and advanced immunology. The role of vaccines remains central to the importance of immunology as a healthcare science – with keystone contributions in the disease areas of smallpox, polio, tuberculosis, measles, mumps, rubella and papillomavirus, amongst many others. CrystalGraphics 3D Character Slides for PowerPoint, - CrystalGraphics 3D Character Slides for PowerPoint. MALT tissues are important in mucosal immune responses, and reflect the particular importance of the gut and airways in immune defence. in mucosal tissues) whilst basophils are found in the blood. Mast cells are tissue resident (e.g. A subset of cytokines, chemokines, play an important role in guiding immune cells to sites of infection by forming a chemical ‘trail’. Title: Basics of Immunology 1 Basics of Immunology 2 This presentation was created by Amelia Farber Sadie Shelton Amy Senestraro Zack Hartman Tanner Hebert This publication was made possible by Grant 024094 from NIAID. Immunology is the study of the mechanisms that organisms use to defend against pathogens and other unwanted matter, including cancer, toxins, and other materials. In addition, autoimmunity occurs when the immune system mistakenly targets self tissues, resulting in chronic inflammatory conditions and tissue destruction. Immunology is the study of the ways in which the body defends itself from infectious agents and other foreign substances in its environment. - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. In addition, another set of receptors, encoded by the major histocompatibility complex (MHC), play an important role in adaptive immunity. A method of inducing artificial immunity by exposing the individual to some portion or form of the pathogen (aka “immunization”): •triggers an adaptive immune response resulting in the production of memory T and B cells specific for antigens from the pathogen Innate immunity comprises both cellular and humoral (‘in solution’) elements. An additional aspect of the maturation process for T cells is that further distinct subsets are produced – helper T cells (also called CD4+ T cells) and cytotoxic T cells (also called CD8+ T cells). Effective regulation of immune responses is also vital to ensure that they don’t themselves cause unnecessary tissue damage, and regulatory T cells (Tregs) are a subset of T cell that play an important role in this process. Immunology charts, mea… Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Dear Biology Aspirants, Here you can find the Lecture Notes in Immunology. MCD Immunology Alexandra Burke-Smith 3 Cells of the innate immune system Granular leukocytes Natural Killer (NK) cells - Identify and kill virus-infected and tumour cells - Complex recognition system- recognise HLA molecule of virus infected cell or tumour, and kill them Macrophages - Mononuclear phagocytes - To main functions: 1. Show me. - The Human Immune System: Basics and then some Basic Components of the Immune System Pathogen, Bacteria, Viruses, Infections, and parasites Leukocytes Antibodies ... - Dr. Colin R.A. Hewitt crah1@le.ac.uk Movie credits: The movies of cells are used with the permission of Dr. James A. Sullivan of Cells Alive http://www.cellsalive.net/, New Issue Released by Journal of Immunology, - Journal of Immunology is a peer-reviewed international online publication which aims to publish articles. Immunology 7. th. Multiple Choice Questions on Basic Immunology Concepts. Show me. Basics in paediatric allergology: IgE-mediated allergy in respiratory illness, - Basics in paediatric allergology: IgE-mediated allergy in respiratory illness Prof. Dieter Koller, M.D. The natural killer (NK) cell is another important innate cell that is able to detect and target intracellular infection of body cells by viruses. All immune cells originate in the bone marrow, deriving from haematopoietic stem cells, but an important set of immune cells (T lymphocytes) undergo maturation in an organ known as the thymus. The cellular elements are represented notably by phagocytes (specifically neutrophils and macrophages) that can respond to signs of infection (i.e. New Issue Released by Journal of Immunology - Journal of Immunology is a peer-reviewed international online publication which aims to publish articles. © The copyright for this work resides with the author, Registered charity - 1043255 in England and Wales / SC047367 in Scotland, and registered in England and Wales as company 3005933, E: BSI@immunology.org Introduction To Immunology And Hematology PPT. 3643-236 Facebook: Antitelija ... - Immunology: Specific Immunity Immunity: not being susceptible to disease Types of immunity Innate: you have it from birth. Examples include: type 1 diabetes, rheumatoid arthritis, and multiple sclerosis. Do you have PowerPoint slides to share? The individual specificity of lymphocytes is key to the generation of adaptive responses. Presentation Summary : Kuby. The thymus and bone marrow are known as primary lymphoid tissues. These are primarily The complement activation pathways are termed: the classical pathway, the alternative pathway, and the mannose-binding lectin pathway. In its most complex forms, the immune system consists of two branches: the innate immune system that utilises certain ‘hard-wired’ strategies to provide a rapid, general, response when alerted by certain typical signals of infection (essentially forming a first-line of defence); and the adaptive immune system that is able to develop highly specific responses (and a persistent ‘immune memory’) to target infection with extraordinary accuracy. A Review On Nk46 the Immunogenetic Predictive Candidate Gene of Unexpplained Recurrent Miscarrages 5. This constitutes the cellular adaptive response. Medi 4318, - Title: Immunology Thermoregulation Nutrition & Metabolism Musculoskeletal Physiology Genetics and Genetic Abnormalities Author: Patricia V. Slater, - Title: The basics of immunohistochemistry Author: ITS Last modified by: vetsetup Created Date: 3/24/2011 4:23:25 PM Document presentation format: On-screen Show (4:3), - LMCC Preparation Back to Basics Neurology Dr. C.R. Th17 cells have recently been identified and are thought to play a further specialised role. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH. presentations for free. The internal mucosal tissues (e.g. Journal of immunology provides current research information in basic and advanced immunology. Gluten and the Gut: A Brief Review of Gluten-Related Gastrointestinal Disorders 3. Disease-causing antigens are called pathogens. Heather Potts . 4. T cells carry T-cell receptors (TCR), whilst B cells carry B-cell receptors (BCR), and variations in the fine structure of these receptors account for the individual specificity described above. Inborn (‘congenital’) immunodeficiencies, with a genetic basis, can disable all, or part, of the immune response (both innate and adaptive) – resulting in vulnerabilities to infection or cancers. The immune system is divided up into two distinct parts: Innate immunity and adaptive immunity. – the study of how the body fights disease and infection. An introduction to immunology and immunopathology Richard Warrington1*, Wade Watson2, Harold L Kim3,4, Francesca Romana Antonetti5 Abstract In basic terms, the immune system has two lines of defense: innate immunity and adaptive immunity. Major APCs are dendritic cells (DCs), which are found throughout the body – however macrophages and B cells may also serve as APCs, with the former providing an important link from innate immunity. Inflammation, as a result of infection, allows plasma, containing complement proteins, to enter infected tissues. • Immunology. It's FREE! However, success can depend on the target pathogen, and effective vaccines for HIV, hepatitis C and malaria remain elusive, in large part due to the mutability of these organisms as targets for the immune system. In both cases, concurrent activation of helper T cells is usually necessary to ensure an effective overall response. Cytokines form an important family of proteins that function as immune mediators and have important roles during immune responses – they can serve to both stimulate or inhibit the differentiation, proliferation or activity of immune cells. If you continue browsing the site, you agree to the use of cookies on this website. The adaptive immune response consists of two branches, a cellular adaptive response (effected by cytotoxic T cells) and a humoral adaptive response (effected by B cells). The selection first elaborates on the basic notions of immunity, antigens, immunoglobulins, and the production of antibody. Key to the adaptive immune response is the lymphocyte. The PowerPoint PPT presentation: "Basics of Immunology" is the property of its rightful owner. Many of them are also animated. It started as a branch of microbiology, which led to the study of infectious diseases and then the body’s response to it. Chapter 1 Pages 1-22 & Chapter 2 Pages 27-57. • Function of defences • Immune response to infection and vaccines • Generating specific immunity • Enhancing the immune defences. It has the ability to discriminate (differentiate) between the individual`s own cells and harmful invading organisms. lungs & airways, and the gut) are coated with mucus that is … It is important to note that an effective primary adaptive response (e.g. In basic terms, the immune system has two lines of defense: innate immunity and adaptive immunity. by Trinity College Dublin A series of 18 graduate level lectures provided by. The former is directed especially towards pathogens that have colonised body cells or body cells that have become malignant (as in cancer). Activated cytotoxic T cells of a given specificity proliferate in the lymph and then migrate to sites of infection where they monitor body cells for signs of intracellular infection or aberrant self proteins associated with cancer –  presented on MHC class I molecules – using  their TCRs. 42:14. Overview. PPT – Basics of Immunology PowerPoint presentation | free to view - id: fd796-ZDc1Z, The Adobe Flash plugin is needed to view this content. Northern California Rheumatology Society (NCRS) 6,494 views. You enable Flash, refresh this page and the regulatory mechanisms utilized by drugs which alter immune response is eosinophil. Cell types including macrophages of infection ( i.e disease and infection by Noel R. Basics. Desired topic to access its contents Basics of Immunology: an Introductory Unit for High School Junior and Students. 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